1st appearance of the Venom Horse
1st appearance of Eganrac, the anti-Carnage
1st appearance of Arachniote, created by Knull
Make storyline comes with venomized horse variant by Clayton Crane.
Three-issue event tie-in
Deadpool bonds with the Princess Symbiote
1st appearance of Flicker, a Symbiote bonded to a host named Lin.